DragonCell is an extract derived from Nothern dragonhead (Dracocephalum ruyshiana) stem cells. It contains high concentration of phenolic substances. Among them >60% are caffeic acid derivatives, including rosmarinic acid and chlorogenic acid. These are well known antioxidants with beneficial biological activities, including anti-inflammatory, anti-ageing and anti-rosacea.

DragonCell boost proliferation of dermal and epidermal cells reversing skin ageing processes. In addition, it stimulates collagen production in the same time inhibiting activity of collagen degrading enzymes.

Effect on skin cell proliferation

DragonCell already at concentrations 0.25% and 0.5% stimulate skin cell growth and division. Just 24h after application it increases proliferation of skin keratinocytes by 24%. Proliferation of dermal fibroblasts is increased by 15% within 48h.

Protects skin from UV-induced stress

DragonCell boosts capability of skin keratinocytes to resist UV light induced stress – after exposure to UVA/UVB viability of keratinocytes preincubated with 1% DragonCell is 27% higher than control. If added after UV-exposure DragonCell contributes to maintenance of skin cell viability due to its anti-radical activity.

Modulation of capillary structures

Rosacea and cuperose are conditions associated with inappropriate proliferation of endothelial cells, dilated blood vessels and changes in permeability of capillaries. DragonCell at concentrations 0.5 and 1% inhibits proliferation of endothelial cells, formation and branching of capillaries. This makes DragonCell a valuable ingredient for anti-cuperose and anti-rosacea applications.

Boosts production of collagen and protects it from degradation

In vitro tests show that DragonCell at concentration range 0.5-1% boosts expression of collagen and in the same time protects it from degradation by inhibiting expression of matrix metalloproteinases.

INCI Water, glycerin, ethanol, Dracocephalum ruyschiana callus culture extract
Ethanol free form: Glycerin, water, Dracocephalum ruyschiana callus culture extract
Key compounds Rosmarinic acid, chlorogenic acid
Efficacy data – (in vitro)
Anti-ageing Skin cell proliferation

Expression of collagen

Anti-inflammatory Expression of MMP-1
Antioxidant Resistance from UV light induced stress
Anti-Rosacea Proliferation of endothelial cells, formation and branching of capillaries
Technical Specification
Appearance Brown liquid
Odour Characteristic (mild)
pH 6.5 ± 0.5 at 25°C
Solubility Water soluble
Total phenolic compounds >400 μg/ml Gallic acid equivalents (Folin-Ciocalteu method)
Recommended use level 0.5%-1%
Shelf life 12 months
Minimal order quantity 0.5 kg

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