Stem cells of juniper contain high concentration of flavonoids, that contribute to specific biological activities. JuniCell has strong anti-ageing and skin protecting activity.
JuniCell promotes collagen production
Even at concentrations as low as 0.5% JuniCell promotes collagen expression in dermal fibroblasts. Collagen synthesis promoting activity contributes to the anti-ageing characteristics of JuniCell.
Antioxidative activity against UV-induced damages
JuniCell protects skin keratinocytes from negative effects ultraviolet light. When tested on skin cells JuniCell boosts cell resistance to UV and promotes cell viability after UV irradiation. The main protective mechanism of JuniCell is prevention of free radical accumulation in skin cells. JuniCell reduces by 44% accumulation of reactive oxygen species in skin keratinocytes after UV irradiation.JuniCell neutralizes not only reactive oxygen species but also scavenges NO radical.
JuniCell regulates expression of proinflammatory cytokines in skin keratinocytes and promotes expression of antioxidant enzyme superoxide disumutase 1 (SOD1). JuniCell shows this inflammation regulatory activity both in unstimulated keratinocytes as well as after stimulation with acne causing bacteria (Propionibacterium acnes).