QuinCell

Photoaging, caused by prolonged exposure to UV radiation, contributes to approximately 90% of the visible alterations observed in the skin. Not only does the skin's appearance undergo transformations, but its structure and functions also change with heightened cumulative UV exposure. UV light triggers oxidative stress, alters gene expression in skin cells, inducing inflammation and an upsurge in collagen-degrading enzymes. These cumulative effects lead to changes that prove challenging to reverse and can potentially lead to skin diseases.

Simultaneously, we are aware of the mood-boosting advantages of sunlight and are eager to enjoy it in a safe manner.

Anti-photoageing activity

Sun exposure is directly linked to the breakdown of collagen and the reduced collagen synthesis leading to extrinsic skin ageing and the formation of wrinkles.

In dermal fibroblasts already after 24h incubation QuinCell reduces production of collagen degrading enzyme MMP-1 in the same time boosting the synthesis of collagen.

Sun protection booster and antioxidant activity

Upon incubating UV-treated cells with QuinCell, it was observed that it enhances collagen expression, maintaining the level of this extracellular matrix-forming protein comparable to that of non-irradiated controls. This observation clearly underscores QuinCell's photoprotective activity, which, coupled with its antioxidative properties and ability to absorb UVA/UVB, positions QuinCell as a promising SPF booster.

Other bioactivities

• A mild effect on melanin production in melanocytes in vitro was observed (reduction of melanin content by up to 20% compared to control).

• Promotes proliferation of both dermal fibroblasts and keratinocytes.